NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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For ESBL GNR coverage, which antibiotic is only indicated for cystitis?

Ceftazidime/avibactam
Fosfomycin
Carbapenems
Cefotetan

The correct answer is: Fosfomycin

For ESBL GNR (Extended-Spectrum Beta-Lactamase Gram-Negative Rod) coverage, when considering antibiotics that are only indicated for cystitis, the correct choice is fosfomycin (Option B). Fosfomycin is an antibiotic that is generally reserved for uncomplicated urinary tract infections (UTIs) such as cystitis. It is a good option for treating ESBL-producing organisms in the urinary tract due to its unique mechanism of action which is different from traditional beta-lactam antibiotics. The other options are commonly used for ESBL GNR coverage but are not limited to only cystitis treatment: - Ceftazidime/avibactam (Option A) is a combination antibiotic that is effective against ESBL-producing organisms in various infections. - Carbapenems (Option C) are broad-spectrum antibiotics that are often considered as a treatment option for ESBL GNR infections. - Cefotetan (Option D) is a cephamycin antibiotic that is not typically used as a first-line treatment for ESBL GNR infections.