NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What class is Disopyramide?

  1. Class 1a

  2. Class 1b

  3. Class 1c

  4. Class III

The correct answer is: Class 1a

Disopyramide belongs to Class 1a of antiarrhythmic drugs. Class 1a drugs have moderate effects on the sodium channels in cardiac cells, leading to a decrease in the rate of depolarization. They are known to have both moderate effects on the action potential duration and the refractory period. This class of drugs is indicated for the treatment of various types of cardiac arrhythmias. Options B and C, Class 1b and Class 1c antiarrhythmic drugs, have different mechanisms of action compared to Disopyramide. Option D, Class III antiarrhythmic drugs, have a distinct mechanism of action involving potassium channel blockade, which is different from Disopyramide's sodium channel effects.

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