NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

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What is the primary action of Aromatase inhibitors like Anastrozole and Letrozole?

Blocking estrogen receptors
Degradation of estrogen receptors
Blocking conversion of androgens to estrogens
Increasing levels of estrogen

The correct answer is: Blocking conversion of androgens to estrogens

Aromatase inhibitors such as Anastrozole and Letrozole primarily work by blocking the conversion of androgens to estrogens. This action inhibits the enzyme aromatase, which is responsible for converting androgens into estrogens. By blocking this conversion process, these medications effectively lower the levels of estrogen in the body. This is particularly useful in conditions where the growth of certain types of breast cancer is dependent on estrogen, as reducing estrogen levels can help slow down the progression of the disease. The other options are not correct because aromatase inhibitors do not directly work on estrogen receptors or their degradation, nor do they increase levels of estrogen in the body.