NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

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Which medication requires a negative pregnancy test before initiation and monthly thereafter for female patients?

Sildenafil (Revatio)
Bosentan (Tracleer)
Riociguat (Adempas)
Ambrisentan (Letairis)

The correct answer is: Riociguat (Adempas)

Riociguat (Adempas) is the correct answer because it is a medication for pulmonary hypertension and has the potential to cause harm to a developing fetus. This is why a negative pregnancy test is required before initiation and monthly thereafter for female patients. Sildenafil (Revatio), Bosentan (Tracleer), and Ambrisentan (Letairis) are all other medications used for pulmonary hypertension. However, they do not require a negative pregnancy test before initiation and monthly thereafter for female patients. This is because they do not have the potential to cause harm to a developing fetus like Riociguat (Adempas) does. Other reasons for the incorrect options may involve differences in drug mechanisms, drug interactions, and potential side effects.