NAPLEX 2025 – 400 Free Practice Questions to Pass the Exam

Question: 1 / 1820

What is a common side effect of Cyclophosphamide and Ifosfamide due to the metabolite acrolein?

Hypertension

QT prolongation

Hemorrhagic cystitis

An acrolein is one of the metabolites of Cyclophosphamide and Ifosfamide that can cause oxidative stress and damage to the bladder, leading to inflammation and hemorrhagic cystitis. Therefore, this is a common side effect of these drugs. Hypertension, QT prolongation, and osteoporosis are not related to the metabolite acrolein and are not commonly associated with these drugs.

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Osteoporosis

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