NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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For acute manic episodes in bipolar disorder, which is considered first-line treatment?

Antipsychotics
Antidepressants
Lamotrigine
Valproate

The correct answer is: Valproate

For acute manic episodes in bipolar disorder, first-line treatment typically involves mood stabilizers such as valproate (option D). Valproate is commonly used in the management of acute mania due to its effectiveness in stabilizing mood and preventing the recurrence of manic episodes. Antipsychotics (option A) are also commonly used in the treatment of acute manic episodes, but mood stabilizers are generally preferred as first-line agents. Antidepressants (option B) are not typically used as monotherapy in bipolar disorder due to the risk of precipitating a manic episode or rapid cycling. Lamotrigine (option C) is more commonly used for the maintenance treatment of bipolar disorder to prevent depressive episodes, rather than for acute manic episodes.