NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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For which drug is a creatinine clearance (CrCl) below 30 NOT recommended to start treatment with?

Genvoya
Dovato
Biktarvy
Atripla

The correct answer is: Biktarvy

A creatinine clearance (CrCl) below 30 indicates poor kidney function. Therefore, it is not recommended to start treatment with a drug that may further decrease kidney function. Genvoya, Dovato, and Atripla all contain tenofovir, which can potentially decrease kidney function. Biktarvy does not contain tenofovir and is therefore the correct answer.