NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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How to calculate grams of carbs covered by 1 unit of regular insulin using the Rule of 450?

450/TDD insulin
500/TDD insulin
1/ARR
(% risk in control group - % risk in treatment group) / % risk in control group

The correct answer is: 450/TDD insulin

The Rule of 450 is a quick way to estimate how many grams of carbs are covered by 1 unit of regular insulin. It states that 450/TDD insulin will give you the number of grams of carbs covered by 1 unit of regular insulin. The other options do not pertain to the Rule of 450 and therefore are incorrect. Option B, 500/TDD insulin, is not applicable to this rule and may be a confused with the Rule of 500, which is used to calculate how many grams of carbs are covered by 1 unit of rapid-acting insulin. Option C, 1/ARR, refers to the Absolute Risk Reduction formula, and option D, (% risk in control group - % risk in treatment group) / % risk in control group, is used for calculating Relative Risk. Therefore, option A is the most appropriate choice for this question.