NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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In the treatment of ascites, what should the ratio of furosemide to spironolactone be?

  1. 20:50

  2. 40:100

  3. 60:150

  4. 80:200

The correct answer is: 40:100

In the treatment of ascites, furosemide (a loop diuretic) and spironolactone (a potassium-sparing diuretic) are commonly used in combination to manage fluid retention. The ratio of these two medications depends on the severity of the condition and the individual patient's response. Option A (2050) may not provide enough diuretic effect to effectively manage ascites. Option C (60:150) and D (80:200) may provide too strong of a diuretic effect and may lead to electrolyte imbalances. Therefore, option B (40:100) is the most appropriate and commonly used ratio of furosemide to spironolactone in the treatment of ascites.