NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What are the adverse effects of G-CSF treatment?

Hypertension
Bone pain
Hair loss
Nausea

The correct answer is: Bone pain

G-CSF (Granulocyte Colony-Stimulating Factor) is commonly used to stimulate the production of white blood cells in patients undergoing chemotherapy or those with certain conditions affecting their immune system. One of the well-known adverse effects of G-CSF treatment is bone pain. This bone pain typically affects the pelvis, sternum, and long bones and occurs due to the rapid increase in the production of white blood cells in the bone marrow. While the other options may be side effects of other medications, they are not typically associated with G-CSF treatment. For instance, hypertension can be a result of various medications, but it is not a common adverse effect of G-CSF. Hair loss is more commonly associated with chemotherapy, and nausea is a common side effect of many medications but not particularly linked to G-CSF treatment.