NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What characterises monophasic formulations (COC)?

  1. No active pills

  2. Variable estrogen doses

  3. Same dose of progestin and estrogen throughout the active pill days

  4. Iron supplement included

The correct answer is: Same dose of progestin and estrogen throughout the active pill days

Monophasic formulations, also known as continuous formulations, are characterized by having the same amount of progestin and estrogen throughout the active pill days. This means that each active pill contains the same fixed dose of hormones, making it easier to track and maintain hormonal balance. Option A, no active pills, is incorrect because monophasic COCs do contain active pills, just with consistent hormone levels. Option B, variable estrogen doses, is incorrect because monophasic COCs have a fixed dosage of both progestin and estrogen. Option D, iron supplement included, is incorrect because iron supplements are not a defining factor for monophasic formulations.