NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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What class of drug is Tamoxifen?

Selective Estrogen Receptor Degrader
Aromatase Inhibitor
Selective Estrogen Receptor Modulator
GnRH Agonist

The correct answer is: Selective Estrogen Receptor Modulator

Tamoxifen is classified as a Selective Estrogen Receptor Modulator (SERM). This type of drug works by binding to estrogen receptors and blocking the effects of estrogen in the body. This is different from the other options, as they have different mechanisms of action. A Selective Estrogen Receptor Degraders (SERDs) not only block the effects of estrogen, but they also degrade the estrogen receptor, leading to a more complete blocking of estrogen signaling. B: Aromatase inhibitors work by blocking the enzyme aromatase, which converts androgens into estrogen, leading to decreased levels of estrogen in the body. D: GnRH (Gonadotropin-releasing hormone) agonists work by initially increasing estrogen levels followed by a decrease in estrogen. However, this is used in a different context than Tamoxifen, which is primarily used in the treatment of breast cancer.