NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

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What does smoking induce that increases the risk of bleeding with warfarin and clopidogrel?

CYP1A2
CYP2D6
CYP3A4
CYP2C19

The correct answer is: CYP1A2

Smoking induces the enzyme CYP1A2, which can lead to increased metabolism of medications like warfarin and clopidogrel. This increased metabolism can result in lower drug levels in the body, reducing their effectiveness and potentially increasing the risk of bleeding. Therefore, smoking can have a significant impact on the pharmacokinetics of these medications. Options B, C, and D (CYP2D6, CYP3A4, CYP2C19) are not directly related to the metabolism of warfarin and clopidogrel in the context described in the question.