NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What drug combination is associated with the treatment Mavyret?

Glecaprevir/Pibrentasvir
Sofosbuvir/Velpatasvir
Grazoprevir/Elbasvir
Paritaprevir/Ritonavir

The correct answer is: Glecaprevir/Pibrentasvir

Mavyret is a fixed-dose combination medication used in the treatment of chronic hepatitis C virus (HCV) infection. The drug combination associated with Mavyret is Glecaprevir/Pibrentasvir. This combination is effective against multiple genotypes of HCV and is indicated for patients without cirrhosis or with compensated cirrhosis. Options B, C, and D are incorrect: - Sofosbuvir/Velpatasvir is another combination used for the treatment of chronic HCV infection, sold under the brand name Epclusa. - Grazoprevir/Elbasvir is a combination used for the treatment of HCV, sold under the brand name Zepatier. - Paritaprevir/Ritonavir is used in combination with Ombitasvir/Dasabuvir for the treatment of HCV and is sold under the brand name Viekira Pak.