NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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What drug interaction increases the effect of warfarin and sulfonylureas?

Fibrates
PCSK9 inhibitors
Bile acid sequestrates
Niacin

The correct answer is: Fibrates

Fibrates are the only suitable answer out of the given options because they can increase the effect of warfarin and sulfonylureas by increasing the risk of bleeding and hypoglycemia, respectively. Fibrates are known to inhibit the metabolism of warfarin and decrease the glucose levels, which can lead to dangerous side effects when combined with sulfonylureas. The other options, such as PCSK9 inhibitors, bile acid sequestrates, and niacin, are not known to have any significant interactions with warfarin or sulfonylureas. Therefore, they are incorrect options.