NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is a common side effect of first-generation antipsychotics?

  1. Weight loss

  2. Anticholinergic effects

  3. Increased energy levels

  4. Decreased cholesterol levels

The correct answer is: Anticholinergic effects

First-generation antipsychotics commonly exhibit anticholinergic side effects. These side effects include dry mouth, blurred vision, constipation, urinary retention, and confusion. Anticholinergic effects result from blocking the action of acetylcholine, a neurotransmitter in the parasympathetic nervous system. Weight loss, increased energy levels, and decreased cholesterol levels are not typically associated with first-generation antipsychotics.

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