NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is a common treatment to prevent emergence reactions with Ketamine use?

Pretreatment with opioids
Pretreatment with benzos
Pretreatment with antacids
Pretreatment with NSAIDs

The correct answer is: Pretreatment with benzos

Pretreatment with benzodiazepines is a common approach to prevent emergence reactions when using Ketamine. Emergence reactions, such as hallucinations, vivid dreams, and delirium, can occur as Ketamine wears off. By administering a benzodiazepine before or during Ketamine administration, the likelihood of these emergence reactions can be reduced. Benzodiazepines have sedative effects and can help mitigate the dissociative effects of Ketamine, leading to a smoother recovery process for the patient. The other options (pretreatment with opioids, antacids, or NSAIDs) are not typically used to prevent emergence reactions associated with Ketamine use.