NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is a function of adsorbents in other excipients?

To prevent brittleness in preparations
To keep powders dry
To reduce surface tension
To prevent degradation

The correct answer is: To keep powders dry

Adsorbents in other excipients help to keep powders dry by absorbing moisture. This is important to maintain the stability and integrity of the preparation, especially in formulations where moisture can lead to degradation or alteration of the product. Adsorbents work by attracting and holding water molecules, thereby preventing the powders from clumping or becoming sticky due to moisture. This function is crucial in ensuring the quality and efficacy of the pharmaceutical product. Regarding the other options: A. Adsorbents do not prevent brittleness in preparations; this is typically the role of plasticizers or emollients. C. Reducing surface tension is not a function of adsorbents. D. While adsorbents can indirectly help prevent degradation by keeping powders dry, their primary function is to absorb moisture rather than directly prevent degradation.