NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Disable ads (and more) with a membership for a one time $2.99 payment

Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

Practice this question and more.

What is a requirement before prescribing Maraviroc (Selzentry)?

Renal function test
Tropism assay
Liver function test
HLA-B*5701 testing

The correct answer is: Tropism assay

Before prescribing Maraviroc (Selzentry), one of the requirements is a Tropism assay. This is because Maraviroc is a CCR5 antagonist that works by selectively blocking the CCR5 receptor on the CD4 cell which HIV uses to enter the cell. Therefore, determining the tropism of the patient’s virus (CCR5-tropic) using a tropism assay is essential before prescribing Maraviroc. The other options are not necessary requirements before prescribing Maraviroc. Renal function testing may be important for other medications but is not specifically required for Maraviroc. Liver function tests are important for monitoring potential hepatotoxicity with various medications, but they are not a specific prerequisite for Maraviroc. HLA-B*5701 testing is typically performed before prescribing abacavir to reduce the risk of a hypersensitivity reaction, but not for Maraviroc.