NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the first line treatment for Hepatitis B?

  1. DAA combination

  2. PEG-INF or NRTI

  3. Supportive care only

  4. Vaccination after infection

The correct answer is: PEG-INF or NRTI

PEG-INF and NRTI are the most common first line treatments for Hepatitis B. DAA combination is usually reserved for patients with co-occurring conditions or who do not respond to PEG-INF and NRTI. Supportive care only is not considered a first line treatment as it does not directly target the virus. Vaccination after infection is not an effective treatment as it only helps prevent future infections. So, the most appropriate and effective option is PEG-INF or NRTI.