NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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What is the recommended action when combining Amiodarone with Warfarin?

Increase Warfarin dose by 30-50%
Decrease Warfarin dose by 30-50%
No action needed
Switch Warfarin to another anticoagulant

The correct answer is: Decrease Warfarin dose by 30-50%

Amiodarone is a medication used to treat irregular heart rhythms, while Warfarin is a blood thinner used to prevent blood clots. These two medications can interact with each other, making it important to carefully manage their dosages when used together. Increasing the dose of Warfarin while taking Amiodarone can lead to an increased risk of bleeding. Similarly, switching to another anticoagulant may not solve the issue, as these medications may also interact with Amiodarone. Therefore, the recommended action is to decrease the Warfarin dose by 30-50% when taking it with Amiodarone to avoid potential complications.