NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the recommended pneumococcal vaccination for individuals with Sickle Cell and Asplenia aged 19-64 years?

  1. PCV20 x1

  2. PCV15 x1, then PPSV23 x1 >/=8 weeks later

  3. Hep A and B

  4. MenB (Bexsero, Trumenba)

The correct answer is: PCV15 x1, then PPSV23 x1 >/=8 weeks later

For individuals with Sickle Cell and Asplenia aged 19-64 years, the recommended pneumococcal vaccination protocol is PCV15 x1 followed by PPSV23 x1 at least 8 weeks later. This two-step vaccination approach helps provide broader protection against various strains of Streptococcus pneumoniae that can cause serious infections in this high-risk population. Option A (PCV20 x1), Option C (Hepatitis A and B), and Option D (MenB vaccines) are not the recommended vaccines for this specific patient population and age group.