NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

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What serious warnings are associated with MAOIs?

  1. Dry mouth and constipation

  2. QT prolongation and falls

  3. DDIs and hypertensive crisis

  4. Weight loss and insomnia

The correct answer is: DDIs and hypertensive crisis

MAOIs (Monoamine oxidase inhibitors) are a group of medications that are known to interact with a wide variety of drugs, foods, and substances. One of the most serious warnings associated with MAOIs is the potential for dangerous drug-drug interactions (DDIs). This is because MAOIs can inhibit the breakdown of certain neurotransmitters in the brain, leading to excess levels that can cause a hypertensive crisis when combined with other medications or foods containing tyramine. These interactions can be life-threatening and therefore require close monitoring and patient education. This is why option C is the correct choice, as it specifically mentions DDIs and hypertensive crisis, which are significant warnings associated with MAOIs.