NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What should be monitored when using immunosuppressants like tacrolimus and cyclosporine?

Liver enzymes only
Blood glucose levels only
Blood pressure only
Nephrotoxicity, worsening/new onset diabetes, worsening lipids, hypertension

The correct answer is: Nephrotoxicity, worsening/new onset diabetes, worsening lipids, hypertension

When using immunosuppressants like tacrolimus and cyclosporine, it is important to monitor a variety of factors such as nephrotoxicity, worsening or new onset diabetes, and worsening lipids, in addition to just liver enzymes, blood glucose levels, or blood pressure. This is because these drugs can affect several different systems in the body and monitoring only one factor may not provide a complete picture of the patient's overall health and potential side effects. Therefore, it is important to monitor all of these factors to ensure the safe and effective use of immunosuppressants.