NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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Which antibiotics are recommended for mild to moderate secondary SBP and cholangitis?

Carbapenems
Cefoxitin, Ertapenem, Moxifloxacin
Pip/Tazo
Vancomycin

The correct answer is: Cefoxitin, Ertapenem, Moxifloxacin

For mild to moderate secondary spontaneous bacterial peritonitis (SBP) and cholangitis, the recommended antibiotics are cefoxitin, ertapenem, and moxifloxacin. These antibiotics are chosen based on their spectrum of activity against the common bacteria involved in these infections. Cefoxitin and ertapenem are effective against a broad range of gram-negative and some gram-positive bacteria, making them suitable choices for these types of infections. Moxifloxacin, a fluoroquinolone, covers gram-negative and some gram-positive organisms as well. Carbapenems (option A) are broad-spectrum antibiotics that are reserved for more severe infections due to concerns about antibiotic resistance and the potential for adverse effects. Pip/Tazo (option C) is commonly used for a variety of infections but may not be the first choice for mild to moderate cases of secondary SBP and cholangitis. Vancomycin (option D) is mainly used for gram-positive infections and is not typically indicated as a first-line treatment for SBP or cholangitis.