NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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Which calcimimetic is used in dialysis patients to decrease PTH, Ca, and PO4?

Cinacalcet
Calcitriol
Etelcalcetide
Calcifediol

The correct answer is: Cinacalcet

Cinacalcet is the correct answer because it is a calcimimetic that is commonly used in dialysis patients to lower parathyroid hormone (PTH), calcium (Ca), and phosphate (PO4) levels. Cinacalcet works by sensitizing the calcium-sensing receptors in the parathyroid gland to calcium, which leads to a decrease in PTH secretion. This helps in managing secondary hyperparathyroidism in patients with chronic kidney disease on dialysis. The other options are incorrect because: - Calcitriol (option B) is a form of Vitamin D and is commonly used to treat Vitamin D deficiency, not specifically to decrease PTH, Ca, and PO4 in dialysis patients. - Etelcalcetide (option C) is another calcimimetic agent used to treat secondary hyperparathyroidism in patients with chronic kidney disease, but it is less commonly used compared to cinacalcet. - Calcifediol (option D) is a prohormone of calcitriol and is also used for treating Vitamin D deficiency, not specifically to decrease PTH, Ca, and PO4 in dialysis patients.