NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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Which drug is associated with a risk of agranulocytosis requiring REMS?

  1. Aripiprazole

  2. Lurasidone

  3. Clozapine

  4. Risperidone

The correct answer is: Clozapine

Clozapine is associated with a risk of agranulocytosis, a potentially life-threatening condition where the body does not produce enough white blood cells. As a result, Clozapine is required to have a Risk Evaluation and Mitigation Strategy (REMS) in place to monitor patients for this side effect. Aripiprazole, Lurasidone, and Risperidone do not carry this risk and therefore do not require REMS.