NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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Which medication is an IL-1 receptor antagonist?

Rituximab
Anakinra
Abatacept
Tocilizumab

The correct answer is: Anakinra

Anakinra is the correct answer because it is an IL-1 receptor antagonist. Anakinra works by competitively inhibiting the binding of interleukin-1 (IL-1) to the interleukin-1 receptor. This action helps to reduce inflammation and is used in conditions such as rheumatoid arthritis and other inflammatory disorders. The other options listed are not IL-1 receptor antagonists. Rituximab is a monoclonal antibody that targets CD20 on B cells. Abatacept is a selective T-cell costimulation modulator that inhibits T cell activation by binding to CD80 and CD86 on antigen-presenting cells. Tocilizumab is a monoclonal antibody that targets the interleukin-6 (IL-6) receptor, not the IL-1 receptor.