NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Study for the NAPLEX exam with a comprehensive quiz featuring multiple-choice questions and in-depth explanations. Build your pharmacological knowledge and increase your chances of passing the pharmacist licensure examination!

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Which medication should not be taken simultaneously with oral Iron?

  1. Aspirin

  2. Quinolone antibiotics

  3. Paracetamol

  4. Statins

The correct answer is: Quinolone antibiotics

Iron can form complexes with many drugs, reducing their absorption in the gastrointestinal tract. Quinolone antibiotics, such as ciprofloxacin, can form chelation complexes with iron, leading to decreased absorption of both the antibiotic and iron. It is advisable to separate the administration of oral iron and quinolone antibiotics by a few hours to avoid this interaction. On the other hand, although some interactions may occur with medications like aspirin, paracetamol, and statins, they do not significantly affect the absorption of iron and can usually be taken together without a significant impact on the effectiveness of the drugs.