NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which of the following intranasal steroids is preferred in pregnancy?

  1. Fluticasone

  2. Triamcinolone

  3. Budesonide

  4. All of the above

The correct answer is: Budesonide

Budesonide is the preferred intranasal steroid in pregnancy because it has the lowest systemic absorption among the options listed, which minimizes the potential risk of fetal exposure. Fluticasone and triamcinolone have higher systemic absorption compared to budesonide, making them less preferable choices during pregnancy. Therefore, budesonide is the safest option for intranasal steroid use in pregnant individuals.