NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which oral acne treatment requires two negative pregnancy tests before starting treatment?

Oral antibiotics
Benzoyl Peroxide
Isotretinoin
Salicylic Acid

The correct answer is: Isotretinoin

Isotretinoin, the correct answer, requires two negative pregnancy tests before starting treatment due to its severe teratogenic effects. Isotretinoin is known to cause serious birth defects if taken during pregnancy, hence the strict requirement for pregnancy tests before initiating treatment. This precaution is crucial to prevent pregnancy while on this medication. It is important for healthcare providers to carefully monitor and educate patients prescribed isotretinoin due to its potential risks. The other options can be ruled out: - Oral antibiotics are not associated with the same strict pregnancy testing requirements as isotretinoin. - Benzoyl peroxide and salicylic acid are topical acne treatments and do not require pregnancy testing before use, making them not the correct answer in this case.