NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which phosphate binder must not be used concurrently with levothyroxine?

Sucroferric oxyhydroxides
Ferric citrate
Calcium acetate
Sevelamer hydrochloride

The correct answer is: Sucroferric oxyhydroxides

Sucroferric oxyhydroxides must not be used concurrently with levothyroxine because it can bind to levothyroxine in the gastrointestinal tract and reduce its absorption. This can lead to decreased effectiveness of levothyroxine, which is used to treat hypothyroidism. On the other hand, the other options (Ferric citrate, Calcium acetate, Sevelamer hydrochloride) do not have a significant interaction with levothyroxine and can be used concurrently if needed.