NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which surfactants are used for topical drug delivery?

Water and glycerin
PEG and poloxamer
Ethanol and water
Bleach and water

The correct answer is: PEG and poloxamer

Surfactants are compounds that are commonly used in topical drug delivery to enhance the absorption of the drug into the skin. Water and glycerin (option A) are commonly used as moisturizers in topical products. However, they do not have significant surfactant properties and would not be effective in enhancing drug delivery. Ethanol and water (option C) are commonly used as solvents, but they do not have surfactant properties and would not enhance drug delivery. Bleach and water (option D) are not used in topical drug delivery at all and can be harmful to the skin. Therefore, the correct answer is option B, as PEG and poloxamer are commonly used surfactants in topical drug delivery.