NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which treatment is NOT recommended for PJP in HIV?

  1. Bactrim

  2. Prednisone for 21 days

  3. Valganciclovir

  4. Atovaquone

The correct answer is: Valganciclovir

Valganciclovir is not recommended for the treatment of PJP (Pneumocystis jirovecii pneumonia) in HIV patients. Valganciclovir is an antiviral medication used to treat cytomegalovirus (CMV) infections, not PJP. A. Bactrim (trimethoprim-sulfamethoxazole), D. Atovaquone, and B. Prednisone are all appropriate treatments for PJP in patients with HIV. Bactrim is the preferred first-line treatment for PJP due to its efficacy and lower cost. Atovaquone can be an alternative for patients who are intolerant to Bactrim. Prednisone, a corticosteroid, is often used as an adjunctive therapy to reduce inflammation in patients with moderate to severe PJP.